Smaxite Intermediate
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Smaxite Is A Gamma-Secretase Inhibitor That Inhibits Beta-Amyloid (A Beta 42), A Beta 38 And A Beta 40, And Ic50 Is 10.9, 12 And 12.1 Nm, Respectively. Inhibiting Notch, Ic50 14.1 Nm, Is A Candidate Drug For Causal Therapy Of Alzheimer'S Disease.
